March 21, 2016

A new paper by Tomasz Suchan and colleagues has been published in PLoS ONE. It presents a novel method of next-generation sequencing-based analysis called hyRAD.

The method benefits from RAD-Seq concept in combination with a hybridization on biotinylated probes. Among its main advantages, it allows obtaining complex and comparable data sets from degraded museum samples. We hope that hyRAD with provide an efficient and relatively cheap method allowing to incorporate large-scale museum sampling in biogeographical and phylogenetic research using NGS.

This study was conducted within the Polish-Swiss Research Programme DRYADE (PSPB–161/10).


Suchan T, Pitteloud C, Gerasimova NS, Kostikova A, Schmid S, Arrigo N, Pajkovic M, Ronikier M, Alvarez N, 2016. Hybridization capture using RAD probes (hyRAD), a new tool for performing genomic analyses on museum collection specimens. PLoS ONE 11(3): e0151651 DOI